Go in prepared: research? the company.

Go to the CRC and do practice interviews. But also do practice informationals. Are there some companies you know a lot about? Some skills you're expert in? If you're a career-switcher, this may be in an area in which you don't plan to continue -- but you can still use your particular strengths for practice! Schedule an informational with a "gimme" and use the opportunity to build your comfort with the format and get prepared for what you'll experience when you're really on the line.